At present also the cholesterol in thinking wrapping dirties is carcinogen via can transforming after bacterial action. Also be the important inducement that causes palace neck cancer. Still discover cervix cancer and the certain virus that make love and infect have particular concern in recent years, be like: Ⅱ of virus of rash of ① mankind scar (HSV, 2) , because of HSV, 2 antibody check ～ of the 80 ％ in the patient in cancer of wellability palace neck 100 ％ are electropositive; Virus of tumour of ② mankind tit (HPV) , undertake HPV particularity antigen to organization of cancer of neck of of all kinds palace detect, all hint of cervix cancer come on with HPV infection is concerned; Virus of afterbirth of ③ mankind large and small (CMV) . All have a story domestic and internationally, drop of antibody of CMV of serum of not typical and proliferous patient spends the pathological change before cervix cancer all tall; Animal experiment proves CMV - DNA is had malign change ability. Accordingly, virus infection makes one of main tasks that study palace neck cancer sends ill reason in recent years.
Pathology change
Cervix cancer with scale shape epithelial cancer is given priority to, occupy 90 ％ ～ about 95 ％ , gland cancer occupies 5 ％ ～ only 10 ％ . But both cancer is on the exterior and do not have special difference, and all happen inside ministry of palace neck vagina or neck canal.
(One) eye view is infiltration cancer in development before, naked eye observation is not had special and unusual, or debaucjed of neck of similar and average a note of the ancient Chinese five-tone scale. As the occurrence of infiltration cancer, palace neck can behave the following 4 sort:
1. Erosion: Surround surface of the mouth outside palace neck has area of coarse grain shape debaucjed, or have break through broken face irregularly, touch easy haemorrhage.
2. Be born outside model: Weigh hyperplasia again model or cauliflower. By polypous appearance or tit state upheaval, then develops the cauliflower shape excrescence that differs to the outstanding size inside the vagina, qualitative fragile easy haemorrhage.
3. Be born inside model: Weigh infiltration again model. Neck of constituent soak, palace is corpulent and deep of neck of cancerous organization palace is hard, but the surface still smooth or only simple table ulcer.
4. Ulcer: No matter outside unripe model or inside unripe model after further progress, cancerous organization is necrotic fall off, form ulcer, whole even cervix is one great empty place is replaced, because often afterwards sends sex appeal to catch, reason fetid secretion eduction. Cervix cancer especially gland cancer also can is in charge of to the neck inside grow, make cervix is become tubbish increase, this also is inside unripe model a kind.
(2) lens is checked
1. Not typical and proliferous: Not typical and proliferous expression is rock-bottom cell hyperplasia, rock-bottom cell not only proliferous, and the cell is arranged reach nucleolus to increase mussily, thick catch, chromatin distributings not equal nucleus is heterogeneous change. Not typical hyperplasia can be divided for light, medium reach spend again.
① spends not typical hyperplasia gently (change I class) : Epithelial arrange a bit disorder, the cell spends different sex gently, different epithelial below 1/3 what hold epithelial layer.
Not typical hyperplasia spends in ② (change Ⅱ class) : Epithelial arrange disorder, different sex is apparent, different epithelial below 2/3 what hold epithelial layer.
③ spends SARS hyperplasia again (change Ⅲ class) : Almost all and epithelial polarity disorder or polarity disappears, remarkable different sex mixes the cell former a cancer is not easy already distinction.
2. Former a cancer: Former a cancer (CIS) says again epithelial inside cancer. Epithelial whole layer polarity disappears, the cell is remarkable different, the nucleus is big, catch greatly, chromatin distributings not all, have nuclear dissension look. But pathological changes still inside the cortex on be confined to, film of not penetrable base, very close to each other infiltrates character. Different cell returns the system of palace neck gland that can enter divide with a hyphen at the end of a line to head a division along mouth of antrum of palace neck gland, cause gland system former some is columnar the cell is multilayer place of cell of different scale shape is replaced, but film of gland body base still keeps complete, this kind of circumstance calls palace neck former a body of gland of cancerous drag in.
3. Lens issues inchoate soak cancer: Inchoate soak cancer is in below lens former on cancerous foundation, can discover cancer cell small group to already wore broken base film accidentally, be like tear shape to invade base film around in pledging, the deepness of infiltration does not exceed 5mm, wide do not exceed 7mm, also do not have cancerous kitchen mutual and shirt-sleeve phenomenon, also do not have encroach qualitative inside when vascular evidence, clinical go up without the feature.
4. Scale shape is epithelial infiltration cancer: Penetrate when cancer cell epithelial base film, encroach a qualitative deepness to exceed 5mm, call scale account epithelial soak cancer. In qualitative inside can appear dendritic, all alone shape, diffuse shape or mew of conglomeration shape cancer. According to pathology section, degree of cancer cell become divided can divide for 3 class:
① I class: Differentiation is good. Have in cancerous mew quite quantitative horn changes an appearance, visible and apparent cancer bead.
② Ⅱ class: Medium become divided (the differentiation degree) of cell of middle-level of the neck that amount to palace, the appearance is changed without clear part in cancerous mew.
③ Ⅲ class: The cellule that did not split up (be equivalent to palace neck ground floor did not split up cellular) .
5. Gland cancer: Gland cancer originates what coverture palace neck provides system of the gland inside the surface and neck canal is columnar and epithelial. When lens check, see gland system structure, there is tit state inside gland antrum even protuberant. Epithelial hyperplasia is gland multilayer, the cell is low, different sex is apparent, see nuclear dissension look. If cancer cell fills gland cavity, when as a result cannot find structure of original gland system, often very difficult gland cancer and become divided undesirable scale cancer is distinguished. When cancer coexists, the cancer that be like gland and scale call cancer of palace neck gland, scale. Cancer of gland, scale is malign rate is high, transfer early, prognostic difference.
(responsibility edits: Luo Ying week)
Young woman often is behaved bleed to contact a gender, happen after or after department of gynaecology is checked. Haemorrhage is measured but much but little, the place that encroachs with focus of a disease, size, encroach hemal circumstance to concern
Cancer of inchoate palace neck often does not have apparent symptom, also ask for without special system, as phlogistic as chronic palace neck without clear distinction, when be being checked sometimes, see palace neck is smooth, be in especially neck of
Because the hair cause of disease about cervix cancer still is not clear about, domestic and international much material confirms, marring too early, early Yo, productive reach the woman with disorder sexual life to have higher sicken rate.
Tumor division expert introduces, inchoate cervix clinical performance of cancer is much not apparent, or the symptom with phlogistic neck of only and similar palace, cause leakage examine easily; Once appear symptom, already developed more terminal. But
Basic symptom: Palace neck cancer is inchoate can not have any symptoms, as the development of the illness the symptom also rises apparently. Main show is: Irregular vagina bleeds (especially after sexual life or after department of gynaecology is checked