One, marring too early, early Yo and pregnant produce frequency the happening of many cervix cancer and sexual life have affinity, patient of cancer of neck of great majority palace is married woman, single patient is extremely scarce. Premature sexual life or incidence of a disease of cancer of neck of palace of woman of Fu of marring too early are remarkable heighten. The sicken rate that marries report of group of coordination of prevention and cure is 20 cancer of Beijing palace neck years old before compares 21 ～ 25 years old the group is 3 times higher, the person that marry later than 26 years old is 7 times taller. At the same time the occurence rate of palace neck cancer is followed produce second increase and increase by degrees, the woman that 7 embryo above compares 2 embryo of １ ～ is 10 times taller above. The person that Anhui report bears 5 embryo above, rate of sicken of palace neck cancer compares 5 embryo the following 5 times taller.
2, palace neck debaucjed, because the physiology of cervix reconciles,crack injury and evaginate the cause on analyse, suffer the element stimulation such as all sorts of physics, chemistry and biology easily, include traumatic, hormone and virus to wait. The sends unripe cervix debaucjed existence relationship of palace neck cancer is close, the person that suffer from palace neck debaucjed, the incidence of a disease of palace neck cancer is higher. Wait for an analysis according to Lin Qiaozhi, have the woman of palace neck debaucjed, occurence rate of palace neck cancer is 0. 73 ％ , 0 what remarkable prep above does not have woman of palace neck debaucjed. 10 ％ . Beijing (1972 ～ 1976) the incidence of a disease that census discovers erosion group is 2 times higher than having erosion group. Palace neck cracks the happening of injury and cancer to also have particular concern.
3, a few clinical data point out wrapping dirty element, wrapping dirty of the person has conclusive effect to the happening of phallic cancer not only, and have affinity with the happening of cervix cancer. Epidemiology considers to prove, the Jew sees those who be less than phallic cancer happen almost, the cervix cancer occurence rate of Jewish woman is very low also at the same time. Other occurence rate of cancer of neck of the palace in be like Moslem woman also inferior. The custom that its reason and Jew and annulus of wrapping of routine of Moslem canon boy cut is concerned. Clew wrapping dirty may be the carry person of virus or chemical carcinogen. Foreign somebody ever caused small rat cervix with human wrapping dirty cancer scores a success. Domestic king Heng Wen confirm person prototype wrapping dirties or wrapping dirties total fat is mixed to small rat cervix the skin has the effect that cause cancer on the vagina. After the action of cholesterol classics bacterium in thinking wrapping dirties at present, can transform for carcinogen.
4, virus element already was sure certain virus can cause animal tumor of late, ceaseless somebody confirms the concern of cervix cancer and herpes virus. In cervix cancer cell, see virus grain, the palace neck that with immune fluorescence antibody law discovers person of palace neck carninomatosis falls off in the cell, contain bleb Ⅱ virus.
In addition, serological research discovers, in cervix cancer patient, the antibody positive rate of bleb Ⅱ virus is as high as 80 ％ left and right sides, and normal woman positive is led only 30 ％ left and right sides. The census such as N Obmias is average Ⅱ of virus of the herpes in the crowd infection rate is 0. 10 ～ 0. 15 ％ , and mix before palace neck cancer increase apparently in cancerous patient. Through to female reproduction Ⅱ herpes virus affects the patient's follow, the occurence rate that discovers palace neck cancer relatively contrast the group is 6 times higher.
In recent years, consider a few more domestic and internationally to make clear, virus of person tit tumour (S of ｕ of ｒ of ｉ of ｈ ｕ ManpapillomaV, abbreviation HPV) concern with the happening of palace neck cancer. For example institute of tumour of Chinese academy of medical sciences, alignment undertakes detecting study related the HPV16 in be being organized to palace neck cancer DNA; Jiangxi college of medicine uses method of PAP immunity enzymatic coloring, organize those who undertake HPV particularity antigen to detect to neck of of all kinds palace, all hint of palace neck cancer come on with HPV infection is concerned.
5, the growth that estrogen of sex hormone element can promote uterus and vaginal organization and exciting palace neck are epithelial and proliferous. Somebody uses benzoic acid female element alone 2 alcohol make small rat causes cervix cancer. Also animal experiment proves, estrogen causes small rat cervix to the carcinogen such as methylic bravery anthracene cancer has stimulative effect. When Yu Mingpeng is studying the hormone of patient of palace neck cancer metabolizes, discover former cancer and a person of carninomatosis of inchoate palace neck, inside make water female 2 alcohol, female ketone and female the scale on the high side of 3 alcohol. Level of the estrogen inside gestation body relatively blame pregnancy is tall 25 ～ 40 times, can make pregnant woman cervix epithelial and remarkable proliferous, happen even similar not typical hyperplasia or former a cancerous change, but postpartum can return to normal gradually.
Anyhow, the true pathogeny of palace neck cancer still is not clear about. Think at present, the put together collaboration of all sorts of elements is used, come on to its have important sense.
(responsibility edits: Luo Ying week)
According to data introduction, palace neck cancer is one of the female's commonnest malignant tumor, see more in 50 years old of above old woman, but hasten of hair ill crowd is young in recent years change, the smallest patient year only 18 years old.
Consider to confirm, the cervix cancer that can prevent type of virus of tumour of tit of 4 kinds of people is vaccinal, the middleaged woman that is opposite 45 years old likewise is effective. Foregone vaccine of this 4 syncretic is right 9 to 16 years
Marring too early, early Yo, productive, marry for many times, sexual spouse is more wait for the female with disorder sexual life, palace is cervical incidence of a disease is higher, this already was in recent years confirmed do not dispute a fact, espe
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Up to now, the pathogeny of palace neck cancer still does not have final conclusion. Most author considers as a variety of elements the result of action, its come on cross frequency, wrapping with debaucjed of neck of marring too early, early Yo, producti
First what cervix cancer ranks cancer occurence rate high, but it is the cancer that only can prevent, want to notice to check at ordinary times only, can be far from a risk.
Palace neck cancer is by palace the neck is mixed by clothe skin gland is epithelial leather malignant tumor. Go up by coverture of leather happening basically is cancer of scale shape cell, abbreviation scale cancer; By gland what epithelial happening is
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