Yang Mou incoming letter says Guangdong Meizhou reader: Male, 83 years old, 2001 diagnose prostate cancer, use hormone of emasculated He Kangxiong to medication, the find oneself after art is good. Detect serum SPA, to 2005 it is all the time before the bottom under 0 accept gram. But after out of service fights androgen to treat, january was checked 2006. SPA rises to be overcome to 0.61 accept suddenly, rose to be overcome to 6.41 accept again in September, rose to be overcome to 7.63 accept in October. The doctor says, 70-79 year old the age paragraph serum SPA can rise naturally to be overcome to 0-6.5 accept (normal value) , if rise to be overcome to 10-20 accept, need to restore to refuse androgen treatment. So, it is normal whether is my current condition belonged to. Ought to resume treatment?

Answer Yang Mou's reader:

The English tag that PSA is prostate particularity antigen is initial logogram. Only prostate is mixed urethral all round gland body is columnar epithelial ability secretes PSA, other organization cell is medium inside body without this material, belong to enzymatic kind of protein. A large number of domestic and internationally detecting the material is certain already, prostate produces canceration, or pathological changes develops further when reaching the recrudesce after curing, chroma of the PSA inside serum just appears undertake the gender lifts phenomenon. So, the PSA in serum is elevatory, it is prostate cancer inchoate diagnose and operation hind, endocrine cure, influence the cure, monitoring index that puts curative effect fruit.

The near future considers to discover, when the injury outside other prostate disease and prostate, content of the PSA in serum also can lift, but combine this 83 years old particular case analyses old gentleman, can be prostate cancer castrate for certain (bilateral spermary is excised) the expression that the illness after art relapses, is not other reason. 1. Old gentleman already was by diagnose in terminal FB, C period) prostate cancer: 2. The patient is made only bilateral spermary resection (clinical on call emasculated operation) . The prostate organization of canceration still is inside body, did not make the other treatment that fight cancer: 3. After art everyday during profess to convinced fights male hormone to treat, serum PSA content is under normal level, instead is intermittent (removed) the gender takes medicine one year to mix PSA of the serum after stopping drug by " 0 " 7 what rise to now gradually, 6 accept are overcome (Ng) -- make clear from this, of content of the PSA in serum undertake the gender lifts develop with canceration, decrease to fight male hormone with out of service closely related. Accordingly, old gentleman cannot sit absolutely wait to continue to the PSA in serum heighten resumes treatment again to above of 10 accept gram, answer to begin the sex hormone fighting hero of full amount to treat instantly. If use,medication so chroma of the PSA in cannot reducing serum, can fall in expert guidance, convert estrogen (if ethylene is female phenol, female 2 alcohol) cure, or estrogen and therapy of combination of the sex hormone that fight hero, change cure or put cure.

With detect acidity phosphoric acid is enzymatic in serum with alkalescent phosphoric acid enzymatic chroma, B exceeds, CT and nuclear magnetism in all the video examination such as shake, OK and real knowledge now pathological changes state, have transfer without cancer cell of the pelvis and organ of organization of vertebral etc far, make other treat plan with benefit.

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(Responsibility edits: Liu Zhenlong)