Expert brief introduction
Bright and, be engaged in surgery of secrete make water working more than 20 years, have job of hospital of 3 level teaching to experience, be good at secrete make water and tumour of system of schoolboy sex breed (prostate cancer, kidney cancer, cystic cancer) , prostate hyperplasia disease and the cure with uric calculous road, have relatively rich clinical experience.
Prostate cancer is the malignant tumor with make water of secrete of Euramerican country male and male reproduction the commonnest system, the 2nd is listed in male cancer mortality, be next to lung cancer. The incidence of a disease of our country prostate cancer is apparent under Euramerican country, but have the tendency that increases apparently in last few years. So, does cancer have terminal prostate is method treated? The answer is affirmative.
Effect a radical cure operation
Effect a radical cure the operation is prostate cancer can achieve cured remedial method exclusively, but be confined to inchoate prostate cancer.
Put cure
Prostate cancer is relatively sensitive to putting cure, to cannot what undergo surgery treats is OK undertake radiating remedial. Put cure to have constant complication, the patient often is able to bear or endure hard suffer. Compare at present putting cure advancedly is to pass the comfortable sex after computer simulation is designed to put cure, its utmost land improved remedial result, reduced the side effect that puts cure at the same time, but the price is high, be not average person to be able to bear.
Endocrine cure
Endocrine cure is the important step that treats prostate cancer, be in clinical on application is very wide. The androgen in human body serum originates spermary and adrenal. The cell inside prostate organization is right the dependence of hormone each are not identical, cancer cell relies on androgen mostly, drop when level of the androgen inside body, cancer cell lost androgen this one environment, cancer cell can die namely, this is the core place that endocrine treats prostate cancer. In a word, endocrine cure is the androgen inside purify or antagonism body, make androgen falls lowermost level, achieve remedial goal thereby. Commonly used method has:
1. Spermary excision
The androgen in human body serum has 90% to originate spermary, 10% originate adrenal, excision spermary goes namely the androgen besides the majority in human body serum, this operation is simple, can undertake below bureau hemp, operation complication is little, it is home's most commonly used treatment method.
2. Hormone of hurried corpus luteum releases hormone analogue (LHRH-A) inject therapeutics
This medicine every all around inject, use consecutively 3? Can fall level of the androgen inside body 4 times lowest, achieve the result that spermary excises, friend calls medicaments castrate again, but this therapeutics is inchoate can make ketone of the Gao in blood elevatory, accordingly, serious to dysuria symptom, bone is painful apparent or the patient of paraplegia is not applicable, because it can cause semiotic accentuation. The biggest advantage of medicaments castrate is to stop level of ketone of the Gao after medicine to be able to pick up gradually, sexual function also restores subsequently, defect is the price costly, cannot use extensively.
3. Block breaks complete androgen cure
Block breaks complete androgen cure makes refuse androgen treatment jointly again, namely operation castrate or medicaments castrate + fight androgen to medication. Much clinical data confirms, to terminal prostate cancerous patient undertakes complete androgen block decides remedy, more emasculated than spermary of pure operation excision or medicaments effect is better. Fight androgen medicaments to have steroid and blame steroid two kinds, steroid kind fight androgen medicaments to have effect of hormone progesterone appearance, side effect is bigger, at present clinical and very few use; is not steroid kind fight androgen medicaments to do not have progesterone appearance action, side-effect is lesser, at present by clinical and wide application, be like fluorine on behalf of medicaments his amine, it is to fight a gleam of that androgen treats to use drug, be brought into cure is protected with medicine. Fluorine common side-effect has his amine breast of mammary ache, male is Nancy etc, have certain effect to hepatic function, most patient can be able to bear or endure suffer, when using drug, should notice to monitor hepatic function.
4. Estrogen
Estrogen passes the endocrine feedback mechanism of human body, restrain the generation of androgen, rise to fight the action of androgen, commonly used medicaments has personal Xi female phenol. Side effect is bigger, current and clinical already used rarely.
Nuclein cure
Nuclein cure basically is used at having bone transferrer, reach the skeletal ache that causes from this apparent person. Nuclein is treated to alleviating bone painful effect is apparent, can cure alleviate 3? 6 months, side effect is little, but charge is more expensive.
Anyhow, person of carninomatosis of most terminal prostate can alleviate through endocrine cure illness, prolong life, improve life quality. Endocrine cure treats the effect with fighting androgen jointly best.
(Responsibility edits: Liu Zhenlong)
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