AFP is abbreviate of triliteral of English Alpha Fetal Protein, meaning plant for armour fetal albumen, albumen of abbreviation armour embryo or fetal armour ball. It is complex of cell of embryonic period liver albumen of a kind of special candy, can promote fetal liver to organize rapid multiplication, the content in reason embryo blood is high, but the about 1 ~ after be born 4 week radical disappear originally, the content in adult blood is very small, qualitative experiment is negative, the most commonly used mensurable experiment (radiative immunity law) normal value is 0 ~ 25ug/L, exceed 25ug/L to be masculine gender, 25 ~ 400ug/L is low density positive, exceed 400ug/L to spend masculine gender for Gao Nong namely.
Cancer of the liver, it is one of our country's commonnest malignant tumor, the king in person cancer! In because clinical hair is uptodate,already was being belonged to more terminal, below the devastate of indulge in wilful persecution of cancerous demon, classics of patient all previous 10 thousand disaster, suffer all kinds of the world to torment eventually hard to avoid dies, spirit of family member susceptive and economically pressure also are average person is adv unimaginably, create the mentality of exceeding to cancer of the liver fear from this. To treat liver cancer effectively, diagnose early discovery, early, early treatment (often say " 3 early " ) it is crucial, and early diagnosing is the most important one link. However, the killer that cancer cell resembles be being concealed in the sea of faces is same, be identified very hard. Come nearly a few years, the scientist did much research, detect with the assay of type of look for a needle in the ocean method, through " killer commits the crime " when stay " clues " come qualitative crack a criminal case. Clinical go up to call this kind of trace " content of cancerous sex mark " , AFP is the mark content with the most distinctive liver cancer. Because hepatic itself is a hematic pool, the cancer that wants 0.2 centimeters to have 0.1 ~ only piece may discover in blood AFP is elevatory, and exceed with B right now, resonance of CT, magnetism those who wait is video learn an examination to still discover hard (normally cancerous bump should be in 1 centimeters to influence ability by video learn to diagnose) certainly.
Accordingly, assay of cancer of the liver checks masculine gender, compare sometimes video learn to check masculine gender to want early a few months to come 1 year or so, this can be won for the patient precious, the remedial time that perhaps is decision destiny! AFP has the value of inchoate diagnostic liver cancer, this is AFP excel the characteristic that other cancer sex indicates content is commendable. Medical personnel is passed detect AFP, in the crowd the sieve is checked or be in clinical on diagnostic liver cancer, take operation or corresponding therapy, already made patient of numerous cancer of the liver is able to prolong life liver cancer of final even conquer. Document data still confirms: In cancer of cell of the former liver that send a gender, the patient AFP of 90% shows 70 ~ electropositive, normally the differentiation degree of the size of the serum chroma of AFP and bump and tumor cell has certain dependency. Normal liver cell does not produce AFP, the liver cell of canceration regains the ability that synthesizes AFP, and the insanity as cancer cell times add, the chroma of AFP can have sexual rise in value. So AFP of patient of cancer of the liver shows positive of durative, high concentration along with course of diseases, be in commonly 400ug /L above. Ever the scholar puts forward: AFP is more than 200ug /L, continuously 8 weeks of above; Perhaps be more than 400ug /L, continuously 4 weeks of above, after the possibility that eliminating gestation and tumour of genital embryo sex, what can make the former liver cancer that send a gender is clinical diagnosed. But, is AFP lifts cancer of the liver certainly? That but not certain! Because still existing,this is the following element:
1. holiday is electropositive: Any examinations are amounted to impossibly 100% correct, AFP determines to also can appear the problem of false positive, did not produce cancer of the liver namely, but AFP shows masculine gender. Answer right now dynamic observation AFP, written guarantee group photo resembles learning those who eliminate to be checked with other laboratory test.
2. is benignLiver disease: The hepatic disease such as cirrhosis of hepatitis of acute hepatitis, chronic activity sex, liver, because virus is duplicate inside liver cell proliferous, make liver cell is in injury, rehabilitate and reborn process, AFP will be elevatory, but concentration is average not quite tall, much under 200ug /L, and as hepatitis improve, AFP also drops subsequently, return to normal gradually then. AFP is elevatory show the characteristic that crosses positive of gender, low density. This conduces to as electropositive as the durative, high concentration of cancer of the liver photograph differentiating. But also have ill patient of a few benign liver, be damaged in great quantities continuously as a result of liver cell and excessive second birth, the fetal armour ball with become divided of reborn liver cell is immature and many synthesis, AFP also can show high concentration positive, its value is more than 400ug /L, have the story that is as high as 6000ug /L even. But if hepatic injury rate is lighter (can wait for liver enzymatic change to observe) through ALT, AST, and AFP lasts high concentration is electropositive, answer the happening of high vigilance liver cancer.
Tumour of 3. embryonic sex: Because AFP has character of biology of cancerous embryo sex, when the gestation, embryonic tumor that has malign reproduction system (wait for) like spermary monster tumour, ovarian cancer, determine AFP will be elevatory, but at this moment due the take a pathological change and lacks cancer of the liver basis as a way of of genital is differentiated.
4. is other: Have a story acid of ammonia of closedown of congenital bravery path, cheese metabolizes the AFP that the disease such as liver cancer of sex of hair of afterwards of unusual, part, hepatic a few benign tumor also has different rate is elevatory.
Of 5.AFP litre fall can regard judgement as prognosis of cancer of the liver or operation and the norm that effects of all sorts of the therapy that fight cancer observe: The operation is adopted to excise after diagnose liver cancer or all sorts of remedy, AFP drops substantially demonstrative treatment is effective, be like after dropping, lift again, adumbrative liver cancer has sign of recrudesce, move.
The place on put together is narrated, AFP is the good target of the liver cancer that monitor, be not to the inchoate diagnostic benefit of small liver cancer especially shallow, but clinical practice is daedal, Protean. Heighten of Chan Ping AFP, it is durative that that is afraid of, high concentration is electropositive, rushed the diagnosis that makes cancer of the liver also is ill-considered, must combine medical history, symptom, reach each assay and video learn data integration analysis, just can make diagnose correctly. So, once is AFP elevatory how should do? True attitude should be: Height takes seriously, need not alarmed. Always AFP is electropositive, especially the second liver of positive of durative high concentration or third liver patient, should regard Gao Wei as the crowd object that monitor, should track observation regularly in the rigor below the doctor's guidance.
(the exercitation edits: Ji Guiyuan)
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