Although evolutional of treatment of cancer of the rectum on current mass rally is large,study the report is less in group randomly, but research of a few forward position, if use all sorts of new technologies,undertake synchronism adds volume mix to put cure by force (IMRT) and biology mark content are forecasted put the curative effect that change cure to wait announced prospective research direction.

As 2004 " magazine of new england medicine " on about Ⅱ / new auxiliary synchronism is put before art of cancer of Ⅲ period rectum after changing cure and method, auxiliary synchronism puts those who change cure to study in group randomly to publish, new auxiliary synchronism is put change cure to already became Ⅱ / the standard of cancer of Ⅲ period rectum treats a method, put the photograph that change cure to compare with the synchronism after art, former and OK the opportunity that reduce local recrudesce to lead further and may make partial patient gets withholding anus, improve its life quality. And how to combine the synchronous medicaments that change cure effectively, forecast new auxiliary synchronism to put the curative effect that changes cure and raise pathology to alleviate completely (the heat that PCR) rate becomes scientists to pay close attention to.

Current mass rally reported the United States is radiative group of remedial oncology coordination (the Ⅱ of RTOG) period clinical research (of RTOG 0012) follow for a long time seek a result. A group of patients accept pyrimidine of 5- fluorine make water (5-FU) vein drips continuously note + pelvic cavity exceeds break up put cure, another group accepts 5-FU vein to drip continuously note + Yi Li is replaced health + pelvic cavity convention is broken up put cure. Although should consider to did not show two groups are related the long-term survival rate, survival rate that do not have tumour and cancer the difference on mortality, but the person that achieve PCR and photograph of the person that did not achieve are compared, can obtain remarkable prolate to live for a long time period, clew obtains PCR is a when the patient is able to live for a long time important and prognostic index.

To achieve tall PCR rate, subsequently and the research that come is about how building a kind to be forecasted reliably mode forecasts a patient to obtain PCR whether likely, 2 be how make through increasing local dosage the patient obtains PCR to the greastest extent.

Prognosis forecasts mode

Buddhist nun of the base of a fruit of Italian tile human relations (the group that Valentini) heads devotes oneself to Ⅱ all the time / new auxiliary synchronism puts cancer of Ⅲ period rectum the research that changes cure, their wall newspaper on current ASTRO conference is paid close attention to. This research compared the clinical data that uses a patient (like the age, sexual distinction, clinical T in installment, tumor length) with use PET/CT to be united in wedlock what clinical data forecasts mode two kinds to forecast new auxiliary synchronism to put PCR of the patient that change cure to lead is different. Consider to show, forecast mode photograph to compare with pure and clinical data, PET/CT+ clinical data can calculate PCR rate better. But because the case load of PET/CT is less (be less than 100) , remain to study further.

Synchronism increases an amount

Increase dosage and raise PCR rate to having inevitable concern it seems that, but the issue that increases dosage to involve two aspects: Piao of Lu of  of star of Huang Qiaowan Wo oh establish of v/LIT an amphora-like jar fears carve Mian bright? 2 it is to increasing dosage while, how to reduce the exposure amount of normal organization effectively.

Belgian scholar uses magnetism resonance to show picture (the dispersion of MRI) adds authority new technology to coach synchronism increases an amount. This research is assisted newly to accepting put 19 patients that turn cure to be divided in what put cure second, undertook dispersion adds authority to scan into the MRI that resemble for many times (the) that be like a graph, those who aim to analyse dispersion to add authority place to show is video divide in rectum cancer there is all without exception to be the same as in second illuminate, resemble undertaking synchronism increases an amount according to increasing advantageous position additionally. This research belongs to biology IMRT category actually. Although should consider to did not show branch an apparent change that rectum cancer dispersion adds authority picture, but the IMRT of biology target area that is rectum cancer offerred a beneficial trial.

Additional, come from American Pittsburgh A to strap case Buddhist nun (a research of Allegheny) total hospital uses PET/CT to become resemble coach the sketch of tumor target area that converts cure is put before rectum cancer art, give synchronism to increase an amount at the same time, also be to achieve higher PCR rate.

Link tone puts cure by force

IMRT has become increasing malignant tumor (cancer of the pharynx that be like bazoo) the mainstream treats a technology, attainable larger local dose, decrease with the best will in the world at the same time all round of normal organization get an amount, but is less.

The expert is applied mediumly in rectum cancer with respect to different technique undertook dosimeter contrast is analysed, think with three-dimensional comfortable form is treated (3D-CRT) photograph is compared, no matter IMRT still is in in target area uniformity respect of normal organization protection all has rise significantly, but 5 wild with 7 wild IMRT and nonsignificant difference. Not come singly but in pairs, on the conference this year, also research thinks, IMRT and 3D-CRT photograph are compared, can reduce small intestine to get the bulk of illuminate of high dose ray significantly, protect normal organization or organ better thereby, avoid to cause serious and undesirable reaction to the patient.

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